The course's objective is understanding the use of pharmacokinetic drug monitoring in choosing the correct dose regimen in the individual patient.
Course Prerequisites
Have followed pharmacokinetic lessons or have pharmacokinetic knowledge.
Teaching Methods
Lectures carried out through presentations (PowerPoint) projected on the screen and possible further information using the blackboard.
Assessment Methods
The exam will be carried out together with the other pharmacology modules 1 in a single test. It will be a written examination consisting of multiple choice and open questions based on didactic material used in the course, carried out in the presence with a PC or other electronic device. The evaluation will be carried out with a weighted average in relation to the number of credits of each part. Graphics is emphasized: students must know how to draw plasma concentration - time curves, etc.
Texts
Laurence Brunton et al., Goodman and Gilman's Le basi farmacologiche della terapia, 13a Edizione, Zanichelli, Bologna, 2019. M. Fuccella, E. Perucca, C. Sirtori - Farmacologia Clinica. UTET 2006. Stephen H. Curry, Robin Whelpton, Introduction to Drug Disposition and Pharmacokinetics 2017 John Wiley & Sons, Ltd
Contents
Therapeutic drug monitoring, definition. Therapeutic ranges and reference ranges. TDM procedure, assay methods. Examples of drugs monitored. Theoretical background needed to make clinically useful TDM. Individual therapeutic concentration. Example of drug with non-linear kinetics.
Course Language
Italian
More information
The lecturer will provide .pdf presentations and other study materials of the topics discussed. It is also available on request for explanations to groups or individual students by appointment.
