ID:
501783
Duration (hours):
8
CFU:
1
SSD:
MALATTIE DEL SANGUE
Year:
2025
Overview
Date/time interval
Secondo Semestre (02/03/2026 - 05/06/2026)
Syllabus
Course Objectives
The student attending this course is expected to acquire fundamental
knowledge of the pathophysiology of blood diseases and their clinical
features, and to learn basic concepts of therapy. Eventually, he/she
should be familiar with the diagnostic approach to the most common
conditions.
knowledge of the pathophysiology of blood diseases and their clinical
features, and to learn basic concepts of therapy. Eventually, he/she
should be familiar with the diagnostic approach to the most common
conditions.
Course Prerequisites
The student should have passed the exam of general physiology.
Principles of general biology, genetics, general patology and immunology
are also required, with particular reference to the mechanisms of
cancerogenesis.
Principles of general biology, genetics, general patology and immunology
are also required, with particular reference to the mechanisms of
cancerogenesis.
Teaching Methods
Lectures, small group teaching, clinical case discussion.
Assessment Methods
Exam modalities
The exam consists of a written test and an oral test, both required. The
written test includes 60 questions, each with five possible answers and
only one correct, to be completed in 120 minutes. In the evaluation of the
written test, the following scores are assigned:
• 1 for each correct answer
• 0 for any failure to reply
• -0.25 for each wrong answer
To be admitted to the oral exam, a student must have obtained a
minimum of 36/60 in the written test. The final score is a weighted
average of written and oral test outcomes.
Exam registration must be done online, while examinations take place in
the classroom located in Clinica Ematologica, inside Fondazione IRCCS
Policlinico San Matteo.
There are 4 exam sessions in any academic year (January-February, June-
July, September, and December), overall with 6 exam dates (2 in January-
February, 2 in June-July, 1 in September, and 1 in December).
The exam consists of a written test and an oral test, both required. The
written test includes 60 questions, each with five possible answers and
only one correct, to be completed in 120 minutes. In the evaluation of the
written test, the following scores are assigned:
• 1 for each correct answer
• 0 for any failure to reply
• -0.25 for each wrong answer
To be admitted to the oral exam, a student must have obtained a
minimum of 36/60 in the written test. The final score is a weighted
average of written and oral test outcomes.
Exam registration must be done online, while examinations take place in
the classroom located in Clinica Ematologica, inside Fondazione IRCCS
Policlinico San Matteo.
There are 4 exam sessions in any academic year (January-February, June-
July, September, and December), overall with 6 exam dates (2 in January-
February, 2 in June-July, 1 in September, and 1 in December).
Texts
Harrison's Principles of Internal Medicine
Contents
Topics to be covered:
1. Bone Marrow and Peripheral Blood
2. Hematopoietic Stem Cells & Growth Factors
3. Hematologic Alterations:
• Erythropoiesis: Anemia and Polycythemia
• Hemostasis: Bleeding and Thrombosis
• Enlargement of Lymph Nodes & Spleen
• Disorders of Granulocytes and Monocytes
4. Erythron, Erythropoietin, and Classification of anemia
5. Aplastic Anemia
6. Iron Metabolism, Iron Deficiency Anemia and Genetic
Hemochromatosis
7. Anemia of Inflammation
8. Megaloblastic Anemias
9. Thalassemia Syndromes
10. Sickle Cell Disease
11. Hemolytic Anemias
12. Myeloproliferative Neoplasms: Chronic Myeloid Leukemia
13. Myeloproliferative Neoplasms: Polycythemia Vera, Essential
Thrombocythemia and Primary Myelofibrosis
14. Myeloid Neoplasms: Myelodysplastic Syndromes
15. Myeloid Neoplasms: Acute Myeloid Leukemia
16. Lymphoid Neoplasms: Acute Lymphoid Leukemia
17. Lymphoid Neoplasms: Hodgkin’s Lymphoma
18. Lymphoid Neoplasms: Malignant Lymphomas
19. Lymphoid Neoplasms: Chronic Lymphatic Leukemia
20. Plasma Cell Neoplasms: Monoclonal Gammopathy of Undetermined
Significance (MGUS), Multiple Myeloma, and Waldenström's
Macroglobulinemia
21. AL Amyloidosis
22. Disorders of Platelets and Vessel Wall:
• Thrombocytopenia (Immune Thrombocytopenic Purpura, Heparin-
Induced Thrombocytopenia, Thrombotic Thrombocytopenic Purpura)
• von Willebrand Disease
23. Coagulation Disorders:
• Hemophilia
• Disseminated Intravascular Coagulation
• Arterial and Venous Thrombosis
• Antiplatelet & Anticoagulant Drugs
24. Transfusion Biology and Therapy
25. Hematopoietic Cell Transplantation
1. Bone Marrow and Peripheral Blood
2. Hematopoietic Stem Cells & Growth Factors
3. Hematologic Alterations:
• Erythropoiesis: Anemia and Polycythemia
• Hemostasis: Bleeding and Thrombosis
• Enlargement of Lymph Nodes & Spleen
• Disorders of Granulocytes and Monocytes
4. Erythron, Erythropoietin, and Classification of anemia
5. Aplastic Anemia
6. Iron Metabolism, Iron Deficiency Anemia and Genetic
Hemochromatosis
7. Anemia of Inflammation
8. Megaloblastic Anemias
9. Thalassemia Syndromes
10. Sickle Cell Disease
11. Hemolytic Anemias
12. Myeloproliferative Neoplasms: Chronic Myeloid Leukemia
13. Myeloproliferative Neoplasms: Polycythemia Vera, Essential
Thrombocythemia and Primary Myelofibrosis
14. Myeloid Neoplasms: Myelodysplastic Syndromes
15. Myeloid Neoplasms: Acute Myeloid Leukemia
16. Lymphoid Neoplasms: Acute Lymphoid Leukemia
17. Lymphoid Neoplasms: Hodgkin’s Lymphoma
18. Lymphoid Neoplasms: Malignant Lymphomas
19. Lymphoid Neoplasms: Chronic Lymphatic Leukemia
20. Plasma Cell Neoplasms: Monoclonal Gammopathy of Undetermined
Significance (MGUS), Multiple Myeloma, and Waldenström's
Macroglobulinemia
21. AL Amyloidosis
22. Disorders of Platelets and Vessel Wall:
• Thrombocytopenia (Immune Thrombocytopenic Purpura, Heparin-
Induced Thrombocytopenia, Thrombotic Thrombocytopenic Purpura)
• von Willebrand Disease
23. Coagulation Disorders:
• Hemophilia
• Disseminated Intravascular Coagulation
• Arterial and Venous Thrombosis
• Antiplatelet & Anticoagulant Drugs
24. Transfusion Biology and Therapy
25. Hematopoietic Cell Transplantation
Course Language
Italian
More information
Please contact the Clinica Ematologica secretariat for further information:
• Phone: 0382-503084
• Phone: 0382-503084
Degrees
Degrees
MEDICINE AND SURGERY
Single-cycle Master’s Degree (6 Years)
6 years
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