ID:
502623
Duration (hours):
8
CFU:
1
SSD:
PATOLOGIA GENERALE
Year:
2025
Overview
Date/time interval
Primo Semestre (01/09/2025 - 16/01/2026)
Syllabus
Course Objectives
During the Pathophysiology course, students will interpret, considering certain types of alterations of integrated functions, physiological changes and adaptive responses of the body following exposure to perturbing agents. At the successful conclusion of this module, you should be able to demonstrate the following course level learning outcomes (CLOs): -CLO.1 Knowledge & Understanding: Demonstrate an understanding of the structure and alterations of four integrated physiological functions. -CLO.2 Ability to Apply Knowledge and Understanding: Apply pathology and pathophysiology concepts to explain the dscribed disease processes, interpret clinical and laboratory data, and use relevant practical skills. -CLO.3 Autonomy of Judgement: Critically evaluate interconnected immune, pathological, and physiological responses. -CLO.4 Communication Skills: Communicate disease pathophysiology effectively in oral and written formats using scientific terminology, and engage professionally in collaborative settings. -CLO.5 Learning Skills: Integrate cross-disciplinary knowledge through lectures, practicals, and online resources to connect basic science with clinical reasoning. This module contributes to the achievement of the following Programme level Learning Outcomes (PLOs) for the “Golgi” degree programme in Medicine and Surgery: -CLO.1 aligns with the Knowledge and Understanding PLO by covering the pahtophysiology of health and disease. -CLO.2 aligns with the Ability to Apply Knowledge and Understanding PLO through application of pathology, pathophysiology, and immunology to interpret lab and case data. -CLO.3 aligns with the Autonomy of Judgment PLO by developing critical evaluation skills of complex disease mechanisms and informed decision-making. -CLO.4 aligns with the Communication Skills PLO by practicing clear written presentation of pathophysiology and engaging in professional discussions. -CLO.5 aligns with the Learning Skills PLO by fostering navigation of structured and independent learning, integration of cross-disciplinary knowledge, and preparation for lifelong self-directed learning.
Course Prerequisites
Basics of chemistry, physics, biochemistry and physiology.
Teaching Methods
The course is taught using lectures and tutorials. The preparation is completed, for students who wish so, through computer simulations of homeostatic alterations.
Assessment Methods
The exam is written and is part of the General Pathology exam. Specifically, for the General Physiopathology course two questions will be asked, one which requires a definition or description, which must be answered with a short essay, and one which requires you to perform an exercise. Each answer will be given a maximum score of two points, the total of which (4 points) will be added to the score of the General Pathology module and the slide to obtain the final grade.
Answers to the questions which, for the definition, are complete and correct and, for the exercise, correctly indicate the final diagnosis will be considered satisfactory.
Answers to the questions which, for the definition, are complete and correct and, for the exercise, correctly indicate the final diagnosis will be considered satisfactory.
Texts
Updated information is available in the course website.
Contents
Topics: General pathophysiology
Homeostasis, functional insufficiency. Alterations in homeostasis of the following functions: psycho-neuro-endocrine-immunological, oxygenation, water and sodium, acid-base and potassium ion.
The General Pathophysiology module of the Harvey course originates from its twin Golgi course counterpart, which has been taught for more than a decade by Prof. Vanio Vannini, my teacher and mentor. This course is largely built on all the teaching material he collected throughout his career and aims first of all at maintaining his vision of the subject.
Object of the course
In this course of General Pathophysiology, some of the most important integrated functions will be analysed. In each chapter, the function itself will be defined and its main regulatory mechanism will be revised. Alterations of the function determined by physiological and pathological conditions will be considered and the corresponding pathophysiological models will be discussed. Reference to the relevant experimental systems will, in fact, be an essential part of the course, as they have been essential to define, or to help define, the pathophysiological mechanisms involved (“how it works”). Reference to the clinics will be also made, as they are expected to be the final theatre where knowledge acquired through the course will be applied in everyday work: knowing how every function works, it should be easier to make sense of the complex reality a patient represents.
In this perspective, this pathophysiology course is meant to contribute a preliminary bridge between laboratory science and the clinics. Particularly, it is studied to give the students the chance to start building relationships between most of the basic disciplines, on one side, and the clinical ones, on the other, where they will get accustomed with “reading” and treating the patient.
Structure of the course
The General Pathology consists of several blocks: some of them will include a single lecture, whereas some others will span several. The first block, Homeostasis, will deal with this basic concept and strictly related ones, which will recur during the course. In the following blocks, alterations of the major integrated functions will be discussed. A consistent structure will be maintained throughout each block: a definition of the function under consideration will be initially given, which will be followed by the list of the organs and systems involved in its regulation and performance, and by the main regulatory mechanisms. A discussion of the alterations of each function and of their clinical significance will be given. Clinical examples will be supplied and exercises will be proposed when considered useful for a better understanding of the key concepts.
Each block of lectures will include the discussion of the alterations of a specific function among the following: Psycho-neuro-endocrine-immunology, Oxygenation, Water and sodium balance, including Oedema, Acid-base and potassium.
Homeostasis, functional insufficiency. Alterations in homeostasis of the following functions: psycho-neuro-endocrine-immunological, oxygenation, water and sodium, acid-base and potassium ion.
The General Pathophysiology module of the Harvey course originates from its twin Golgi course counterpart, which has been taught for more than a decade by Prof. Vanio Vannini, my teacher and mentor. This course is largely built on all the teaching material he collected throughout his career and aims first of all at maintaining his vision of the subject.
Object of the course
In this course of General Pathophysiology, some of the most important integrated functions will be analysed. In each chapter, the function itself will be defined and its main regulatory mechanism will be revised. Alterations of the function determined by physiological and pathological conditions will be considered and the corresponding pathophysiological models will be discussed. Reference to the relevant experimental systems will, in fact, be an essential part of the course, as they have been essential to define, or to help define, the pathophysiological mechanisms involved (“how it works”). Reference to the clinics will be also made, as they are expected to be the final theatre where knowledge acquired through the course will be applied in everyday work: knowing how every function works, it should be easier to make sense of the complex reality a patient represents.
In this perspective, this pathophysiology course is meant to contribute a preliminary bridge between laboratory science and the clinics. Particularly, it is studied to give the students the chance to start building relationships between most of the basic disciplines, on one side, and the clinical ones, on the other, where they will get accustomed with “reading” and treating the patient.
Structure of the course
The General Pathology consists of several blocks: some of them will include a single lecture, whereas some others will span several. The first block, Homeostasis, will deal with this basic concept and strictly related ones, which will recur during the course. In the following blocks, alterations of the major integrated functions will be discussed. A consistent structure will be maintained throughout each block: a definition of the function under consideration will be initially given, which will be followed by the list of the organs and systems involved in its regulation and performance, and by the main regulatory mechanisms. A discussion of the alterations of each function and of their clinical significance will be given. Clinical examples will be supplied and exercises will be proposed when considered useful for a better understanding of the key concepts.
Each block of lectures will include the discussion of the alterations of a specific function among the following: Psycho-neuro-endocrine-immunology, Oxygenation, Water and sodium balance, including Oedema, Acid-base and potassium.
Course Language
Italian
More information
The teacher is available for discussion on the material of the course upon appointment taken by telephone or email. Furthermore, all indications regarding the inclusion of students with particular conditions will be applied, in order to allow them to study for the exam preparation.
Degrees
Degrees
MEDICINE AND SURGERY
Single-cycle Master’s Degree (6 Years)
6 years
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