Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer
Articolo
Data di Pubblicazione:
2019
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Aromatase; Aromatase inhibitors; Breast cancer; Cytochromes P450; Docking; Mixed inhibition mechanism; Molecular dynamics; Resistance onset; Allosteric Regulation; Antineoplastic Agents; Aromatase; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship; Drug Design
Elenco autori:
Spinello, A.; Martini, S.; Berti, F.; Pennati, M.; Pavlin, M.; Sgrignani, J.; Grazioso, G.; Colombo, G.; Zaffaroni, N.; Magistrato, A.
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