Drugs in early clinical development.

The thoroughly revised, updated Fifth Edition of this classic is the most comprehensive, current, and authoritative reference on all anticonvulsants available today. This edition features detailed profiles of newer drugs--including levetiracetam, oxcarbazepine, tiagabine, topiramate, and zonisamide--and new chapters on use of antiepileptic drugs in children and during pregnancy.Drugs are covered in alphabetical order and in an easy-to-follow format: mechanisms of action; chemistry, biotransformation, and pharmacokinetics; interactions; clinical efficacy and use; and adverse effects. Coverage of clinical use includes nonepileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.
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