Multiple mechanisms underlying the neuroprotective effects of antiepileptic drugs against in vitro ischemia
Articolo
Data di Pubblicazione:
2006
Abstract:
The possible neuroprotective effects of classic and new antiepileptic drugs on the electrophysiological changes induced by in vitro ischemia on striatal neurons were investigated. In particular, the aim of the study was to correlate the putative neuroprotective effects with the action of these drugs on fast sodium (Na+) and high-voltage-activated (HVA) calcium (Ca2+) currents.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Rats; Animals; Carbamazepine; Excitatory Postsynaptic Potentials; Fructose; Potassium; Brain Ischemia; Electrophysiology; Valproic Acid; Calcium Signaling; Anticonvulsants; Ion Transport
Elenco autori:
Costa, C; Martella, G; Picconi, B; Prosperetti, C; Pisani, A; Di Filippo, M; Pisani, F; Bernardi, G; Calabresi, P
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