Data di Pubblicazione:
2008
Abstract:
The present invention relates to a screening method for the identification of new nitrobenzothiazinone drugs for the treatment of tuberculosis, which are not or are slowly transformed and inactivated by nitroreductase. The use of the nitroreductase NfnB from M. smegmatis in cancer therapy, and in bioremediation are comprised as well.
Tipologia CRIS:
6.1 Brevetto
Keywords:
Tuberculosis; Nitroreductase; benzothiazinones; drug resistance
Elenco autori:
Riccardi, Giovanna; Manina, Giulia; Pasca, MARIA ROSALIA
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