Publication Date:
2008
abstract:
The present invention relates to a screening method for the identification of new nitrobenzothiazinone drugs for the treatment of tuberculosis, which are not or are slowly transformed and inactivated by nitroreductase. The use of the nitroreductase NfnB from M. smegmatis in cancer therapy, and in bioremediation are comprised as well.
Iris type:
6.1 Brevetto
Keywords:
Tuberculosis; Nitroreductase; benzothiazinones; drug resistance
List of contributors: