Retrospective analysis of 521 endosseous implants placed under antibiotic prophylaxis and review of literature

Antibiotic prophylaxis in surgical implants has not a consensus in the scientific world. This is due both to reports and statistical studies with contradictory results, both to the risk of severe anaphylactic reactions and the emergence of antibiotic resistance and, finally, to the lack of published RCTs. The purpose of this study is to retrospectively analyze and assess the success of surgical therapy with endosseous implants inserted under antibiotic prophylaxis at the Department of Oral Sciences "S. Palazzi", University of Pavia. The data presented are compared to those published in international literature. The work is complemented by a statistical data analysis in order to propose a statistically valid judgement on the effectiveness of antibiotic prophylaxis in preventing postoperative infections.