Data di Pubblicazione:
1999
Abstract:
We studied the effect of Bacille Calmette-Guerin (BCG) vaccine as an immunomodulator in MS. According to the guidelines for clinical trials in MS, a single crossover, MRI-monitored trial was performed in 14 patients with relapsing-remitting MS. After treatment, MRI activity was significantly reduced. No major adverse effects were reported. Adjuvant therapy with BCG vaccine was safe and merits study in MS.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Adjuvants; Immunologic; therapeutic use, Adult, BCG Vaccine; therapeutic use, Brain; pathology, Cross-Over Studies, Female, Humans, Magnetic Resonance Imaging, Male, Multiple Sclerosis; diagnosis/drug therapy/physiopathology, Recurrence, Treatment Outcome
Elenco autori:
G., Ristori; M. G., Buzzi; U., Sabatini; E., Giugni; Bastianello, Stefano; F., Viselli; C., Buttinelli; S., Ruggieri; C., Colonnese; C., Pozzilli; M., Salvetti
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