1-O-, 2-O- and 3-O-beta-glycosyl-sn-glycerols: Structure-anti-tumor-promoting activity relationship

The inhibitory activity of synthetic glycosylglycerols on Epstein-Barr virus early antigen (EBV-EA) activation was evaluated. Among the series of 1-O-, 2-O- and 3-O- glycosylglycerols rested, 1-O-beta-D-galactopyranosyl-sn-glycerol showed the highest inhibitory effect toward tumor promotion. (C) 1996. Elsevier Science Ltd