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Isolation and characterization of a carrot cell line resistant to methotrexate.

Articolo
Data di Pubblicazione:
1984
Abstract:
A carrot cell line (WCA1) resistant to Mtx has been isolated and partially characterizaed. The IC50-Mtx is about thirty times higher in the resistant than in the parental line and the rate of uptake of Mtx is decreased 14 times. In addition the specific activity of DHFR is about three times higher in the resistant line as compared to the parent
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Methotreaxte resistance; dihydrofolate reductase; methterxate uptake; plant cell suspension culture; Daucus carota
Elenco autori:
Cella, Rino; Albani, D; Biasini, Mg; Carbonera, D; Parisi B., 1390 1397
Link alla scheda completa:
https://iris.unipv.it/handle/11571/461501
Pubblicato in:
JOURNAL OF EXPERIMENTAL BOTANY
Journal
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