Effects of premature anodal stimulations on cardiac transmembrane potential and intracellular calcium distributions computed by anisotropic Bidomain models

We investigate by means of 3D Bidomain simulations the Vm and Cai patterns after a premature S2 anodal pulse. The Cai spatial distribution presents a configuration similar to the VEP pattern of Vm. The Cai decrease in the virtual anode is mainly due to the outflow of calcium ions produced by the NCX exchanger