Headache and comorbidity in children and adolescents.

Headache is one of the most common neurological symptom reported in childhood and adolescence, leading to
high levels of school absences and being associated with several comorbid conditions, particularly in neurological,
psychiatric and cardiovascular systems. Neurological and psychiatric disorders, that are associated with migraine, are
mainly depression, anxiety disorders, epilepsy and sleep disorders, ADHD and Tourette syndrome. It also has been
shown an association with atopic disease and cardiovascular disease, especially ischemic stroke and patent foramen
ovale (PFO).