To provide an advanced knowledge of innovative drug delivery systems (DDS) with a particular focus on targeted and site-specific DDS; to develop skills in understanding and discussing case studies of the relevant literature.
Course Prerequisites
Basic knowledge of conventional and modified-release drug delivery systems.
Teaching Methods
Frontal lessons. Reading and discussion of scientific papers.For students with specific needs, who have applied for Inclusive Teaching Methods, adequate teaching material will be available for a profitable independent study. If requested, self-learning can be supported by tutoring or supplementary teaching activities, or by dedicated meetings, also online, with flexible timing depending on the needs.
Assessment Methods
Discussion of a case study reported in the relevant literature.The case study will be chosen by the student among those proposed by the teacher.
Texts
Materials prepared and provided by the teacher.
Contents
Bio-mucoadhesion: definition, theory, measuring systems. Mucoadhesive polymers characterized by penetration enhancement and enzyme inhibition properties. Bio-mucoadhesive systems for ocular, nasal, buccal, oral and vaginal application. Examples of commercial and under study systems. Mucoadhesive and mucopenetrating nanoparticles. Combined strategy: mucopenetrating nanoparticles in mucoadhesive formulations. In situ-gelling systems. Microneedles. Lipid nanoparticles-mediated delivery of mRNA vaccines. Polymer-lipid hybrid nanoparticles. Stimuli-responsive nanoparticles. Surface functionalization of nanoparticles for targeted drug delivery. Electrospun nano fibers for tissue repair and regeneration.
Course Language
Italian
More information
The teacher is available in her office for explanations by appointment by e-mail.
